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DMJ-I-228
CAS No. 1374035-59-2
DMJ-I-228( +)-DMJ-I-228 )
Catalog No. M11542 CAS No. 1374035-59-2
A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDMJ-I-228
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NoteResearch use only, not for human use.
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Brief DescriptionA small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
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DescriptionA small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
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In Vitro——
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In Vivo——
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Synonyms+)-DMJ-I-228
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV
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Research Area——
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Indication——
Chemical Information
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CAS Number1374035-59-2
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Formula Weight435.84
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Molecular FormulaC19H19ClFN5O4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NC1=CC=C(Cl)C(F)=C1)C(N[C@@H]2[C@@H](NC(N)=N)CC3=C2C=CC=C3)=O.O=CO
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Chemical NameN1-(4-chloro-3-fluorophenyl)-N2-((1S,2S)-2-guanidino-2,3-dihydro-1H-inden-1-yl)oxalamide formate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Madani N, et al. Structure. 2008 Nov 12; 16(11):1689-701.
2. Richard J, et al. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94.
3. LaLonde JM, et al. J Med Chem. 2012 May 10;55(9):4382-96.
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