Cart
sales@molnova.com
SB-699393
CAS No. 1348166-93-7
SB-699393( SB699393 )
Catalog No. M11412 CAS No. 1348166-93-7
SB-699393 is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSB-699393
-
NoteResearch use only, not for human use.
-
Brief DescriptionSB-699393 is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM.
-
DescriptionSB-699393 is a potent, selective and CNS penetrant B-Raf inhibitor with Kd of 7.2 nM; possesses enhanced CNS penetration (BB ratio=0.8:1) compared with SB-590885.
-
In Vitro——
-
In Vivo——
-
SynonymsSB699393
-
PathwayMAPK/ERK Signaling
-
TargetRaf
-
RecptorRaf
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1348166-93-7
-
Formula Weight403.482
-
Molecular FormulaC24H25N3O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(E)-((5-(5-(morpholinomethyl)-2-(pyridin-4-yl)furan-3-yl)-2,3-dihydro-1H-inden-1-ylidene)amino)methanol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Takle AK, et al. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4373-6.
molnova catalog
related products
-
3-Indolebutyric acid
3-Indolebutyric acid(IBA) is a plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.
-
Effusanin A
Effusanin A has antibacterial activity. It exhibits DNA-damaging activity in assay which employed DNA-repair deficient (RAD 52Y) and repairs proficient (RAD +) yeast strains. Effusanin A shows inhibitory effects on DU145 cells with IC50 value of 3.16 μM, and LoVo cells with IC50 value of 3.02 μM.
-
PLX-7904
A potent and selective BRaf inhibitor with IC50 of 5 nM against BRaf V600E in mutant RAS expressing cells.
