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Lobeline hydrochloride
CAS No. 134-63-4
Lobeline hydrochloride( Lobeline hydrochloride )
Catalog No. M11393 CAS No. 134-63-4
Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 29 | In Stock |
|
| 50MG | 41 | In Stock |
|
| 100MG | 74 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLobeline hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionLobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
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DescriptionLobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes.
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In Vitro——
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In VivoAnimal Model:Sprague-Dawley rats (200-250 g) Dosage:0.3 mg/kg, 1.0 mg/kg, and 3.0 mg/kg for acute administration; 3 mg/kg for chronic administration Administration:Subcutaneous injection; 15 min prior to measurement, or every 15 min for 7 sessions; separated by 2 intervening maintenance days of d-methamphetamine (0.05 mg/kg/infusion) self-administration Result:Decreased d-methamphetamine Self-Administration.
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SynonymsLobeline hydrochloride
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptornAChR| Nicotinic Receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number134-63-4
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Formula Weight273.92
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Molecular FormulaC22H27NO2·HCl
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Purity>98% (HPLC)
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SolubilityWater: 1g/40mL
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SMILESCN1[C@@H](CC(C2=CC=CC=C2)=O)CCC[C@H]1C[C@H](O)C3=CC=CC=C3.[H]Cl
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Chemical Name2-[(2R,6S)-6-[(2S)-2-Hydroxy-2-phenylethyl]-1-methylpiperidin-2-yl]-1-phenylethanone hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Meyer AC, et al. J Neurochem. 2013 Oct;127(2):187-98.
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