Cart
sales@molnova.com
NOD-IN-1
CAS No. 132819-92-2
NOD-IN-1( —— )
Catalog No. M11309 CAS No. 132819-92-2
A potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 93 | In Stock |
|
| 5MG | 103 | In Stock |
|
| 10MG | 154 | In Stock |
|
| 25MG | 296 | In Stock |
|
| 50MG | 421 | In Stock |
|
| 100MG | 612 | In Stock |
|
| 200MG | 855 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNOD-IN-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively.
-
DescriptionA potent, dual inhibitor of NOD1 and NOD2 with IC50 of 5.74 uM and 6.45 uM, respectively; is 7-fold less potent than Noditinib-1 in terms of NOD1 inhibition and completely devoid of selective activity for NOD1 or NOD2 as opposed to Noditinib-1.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayNF-κB
-
TargetNOD
-
RecptorNOD1|NOD2
-
Research AreaInflammation/Immunology
-
Indication——
Chemical Information
-
CAS Number132819-92-2
-
Formula Weight343.3969
-
Molecular FormulaC18H17NO4S
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(C(N1S(=O)(C2=CC=C(C)C=C2)=O)=CC3=C1C=CC=C3)OCC
-
Chemical Name1H-Indole-2-carboxylic acid, 1-[(4-methylphenyl)sulfonyl]-, ethyl ester
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ke?ek Ple?ec K, et al. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234.
molnova catalog
related products
-
JC-171
JC-171 is a selective NLRP3 inflammasome inhibitor that inhibits LPS/ATP-induced IL-1β release from macrophages with IC50 of 8.45 uM.
-
Dapansutrile
Dapansutrile is a potent, selective and orally active NLRP3 inflammasome inhibitor, with Anti-inflammatory and analgesic activity.
-
NLRP3-IN-10
NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM.
