BI 639667( BI639667 | BI-639667 )

Catalog No. M11194 CAS No. 1295298-26-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

BI 639667
Note

Research use only, not for human use.
Brief Description

BI 639667 (BI639667) is a potent and selective antagonist of human CCR1 with binding IC50 of 5.4 nM.
Description

BI 639667 (BI639667) is a potent and selective antagonist of human CCR1 with binding IC50 of 5.4 nM, inhibits chemotaxis with IC50 of 2.4 nM; shows good physico-chemical and pharmacokinetic properties.
In Vitro

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In Vivo

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Synonyms

BI639667 | BI-639667
Pathway

GPCR/G Protein
Target

Chemokine Receptor
Recptor

Chemokine Receptor
Research Area

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Indication

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CAS Number

1295298-26-8
Formula Weight

451.476
Molecular Formula

C22H18FN5O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 10 mg/mL (22.15 mM)
SMILES

O=C(C1=CN=CC2=C1C=NN2C3=CC=C(F)C=C3)NC4(C5=CC(S(=O)(C)=O)=NC=C5)CC4
Chemical Name

1-(4-fluorophenyl)-N-(1-(2-(methylsulfonyl)pyridin-4-yl)cyclopropyl)-1H-pyrazolo[3,4-c]pyridine-4-carboxamide