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Gingerenone A

CAS No. 128700-97-0

Gingerenone A( AS-HK014 | AS HK014 | ASHK014 | Gingerenone A | Gingerenone-A )

Catalog No. M11170 CAS No. 128700-97-0

A dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
10MG 39 In Stock
25MG 72 In Stock
50MG 129 In Stock
100MG 222 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Gingerenone A
  • Note
    Research use only, not for human use.
  • Brief Description
    A dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells.
  • Description
    A dual inhibitor of JAK2 and S6K1 pathways, selectively kills cancer cells while exhibiting minimal toxicity toward normal cells; induces apoptosis in cancer cells and suppresses tumor growth in vivo associated with relative phosphorylation levels of JAK2 and S6K1; suppresses obesity and adipose tissue inflammation in high-fat diet-fed mice.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AS-HK014 | AS HK014 | ASHK014 | Gingerenone A | Gingerenone-A
  • Pathway
    Angiogenesis
  • Target
    JAK
  • Recptor
    JAK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    128700-97-0
  • Formula Weight
    356.418
  • Molecular Formula
    C21H24O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (280.58 mM)
  • SMILES
    O=C(/C=C/CCC1=CC=C(O)C(OC)=C1)CCC2=CC=C(O)C(OC)=C2
  • Chemical Name
    4-Hepten-3-one, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Byun S, et al. J Biol Chem. 2015 Sep 25;290(39):23553-62. 2. Kim HJ, et al. J Cell Biochem. 2018 Jan;119(1):260-268. 3. Suk S, et al. Mol Nutr Food Res. 2017 Oct;61(10).
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