ML167

CAS No. 1285702-20-6

ML167( ML-167 | ML 167 )

Catalog No. M11167 CAS No. 1285702-20-6

A potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 43 In Stock
2MG 28 In Stock
5MG 40 In Stock
10MG 65 In Stock
25MG 138 In Stock
50MG 230 In Stock
100MG 342 In Stock
200MG 486 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ML167
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B.
  • Description
    A potent, selective CDC-like kinase 4 (CLK4) inhibitor with IC50 of 136 nM, >10-fold selectivity over Clk1, Clk2, Clk3, Dyrk1A/1B.
  • In Vitro
    ML167 has cell permeability in Caco-2 cells. ML167 contains a furan ring which liable to in vivo metabolism.
  • In Vivo
    ——
  • Synonyms
    ML-167 | ML 167
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    CLK
  • Recptor
    CLK1|CLK2|CLK4|Dyrk1B
  • Research Area
    Other Indications
  • Indication
    ——

Chemical Information

  • CAS Number
    1285702-20-6
  • Formula Weight
    335.363
  • Molecular Formula
    C19H17N3O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 62 mg/mL (184.9 mM); Ethanol: 11 mg/mL (32.8 mM); Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1
  • Chemical Name
    5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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