Cart
sales@molnova.com
Neladenoson dalanate hydrochloride
CAS No. 1239235-25-6
Neladenoson dalanate hydrochloride( BAY 10-67197 )
Catalog No. M10960 CAS No. 1239235-25-6
Neladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameNeladenoson dalanate hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionNeladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.
-
DescriptionNeladenoson dalanate is a potent, selective, orally acitve partial adenosine A1 receptor (A1AR) agonist (EC50=0.1 nM) for the treatment of chronic heart failure.Heart Failure Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsBAY 10-67197
-
PathwayApoptosis
-
TargetAdenosine Receptor
-
RecptorAdenosine Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1239235-25-6
-
Formula Weight752.73
-
Molecular FormulaC35H35Cl2N7O4S2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESC[C@@H](C(OCCOC1=CC=C(C2=C(C#N)C(SCC3=CSC(C4=CC=C(Cl)C=C4)=N3)=NC(N5CCCC5)=C2C#N)C=C1)=O)NC([C@H](C)N)=O.[H]Cl
-
Chemical Name2-{4-[2-({[2-(4-chlorophenyl)-1,3-thiazol- 4-yl]methyl}sulfanyl)-3,5-dicyano-6-(pyrrolidin-1-yl)pyridin- 4-yl]phenoxy}ethyl L-alanyl-L-alaninate hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Meibom D, et al. ChemMedChem. 2017 May 22;12(10):728-737.
2. Voors AA, et al. J Clin Pharmacol. 2017 Apr;57(4):440-451.
molnova catalog
related products
-
Binodenoson
Binodenoson is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging.
-
N6-(2-Phenylethyl)ad...
N6-(2-Phenylethyl)adenosine is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM for rat and human A1.
-
Preladenant
A potent and highly selective A2A receptor competitive antagonist with Ki of 1.1 nM.
