NC-001

CAS No. 1237540-68-9

NC-001( NC 001 | NC001 | az-NC-001 )

Catalog No. M10954 CAS No. 1237540-68-9

NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    NC-001
  • Note
    Research use only, not for human use.
  • Brief Description
    NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1).
  • Description
    NC-001 (NC 001, NC001, az-NC-001) is a potent, specific, cell-permeable inhibitor of immunoproteasome caspase-like sites (β1i and β1), does not correlate with inhibition of chymotrypsin-like sites.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NC 001 | NC001 | az-NC-001
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Proteasome
  • Recptor
    Proteasome
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1237540-68-9
  • Formula Weight
    535.646
  • Molecular Formula
    C25H41N7O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (S)-1-((2-azidoacetyl)-L-alanyl)-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxohexan-2-yl)pyrrolidine-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Britton M, et al. Chem Biol. 2009 Dec 24;16(12):1278-89. 2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209.
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