Cart
sales@molnova.com
LR-510444
CAS No. 1233948-35-0
LR-510444( ELR510444 | ELR-510444 | ELR 510444. )
Catalog No. M10927 CAS No. 1233948-35-0
ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 40 | In Stock |
|
| 5MG | 29 | In Stock |
|
| 10MG | 38 | In Stock |
|
| 25MG | 69 | In Stock |
|
| 50MG | 114 | In Stock |
|
| 100MG | 184 | In Stock |
|
| 200MG | 276 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLR-510444
-
NoteResearch use only, not for human use.
-
Brief DescriptionELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.
-
DescriptionELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines.
-
In Vitro——
-
In Vivo——
-
SynonymsELR510444 | ELR-510444 | ELR 510444.
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetMicrotubule/Tubulin
-
RecptorMicrotubule disruptor
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1233948-35-0
-
Formula Weight368.47
-
Molecular FormulaC19H16N2O2S2
-
Purity>98% (HPLC)
-
SolubilityDMSO: 10 mM
-
SMILESO=S(C1=CC=C(C)C=C1)(NC2=CC(C3=CC=C(C#N)S3)=CC=C2C)=O
-
Chemical NameN-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Risinger AL, et al. J Pharmacol Exp Ther. 2011 Mar;336(3):652-60.
molnova catalog
related products
-
Isosorbide Mononitra...
Isosorbide mononitrate is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.
-
Plocabulin
Plocabulin (PM060184) is a novel tubulin-binding agent binding to αβ-tubulin dimer with nanomolar affinity.
-
KIF18A-IN-2
KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.
