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LR-510444
CAS No. 1233948-35-0
LR-510444( ELR510444 | ELR-510444 | ELR 510444. )
Catalog No. M10927 CAS No. 1233948-35-0
ELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | In Stock |
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| 5MG | 58 | In Stock |
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| 10MG | 87 | In Stock |
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| 25MG | 176 | In Stock |
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| 50MG | 332 | In Stock |
|
| 100MG | 478 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLR-510444
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NoteResearch use only, not for human use.
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Brief DescriptionELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.
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DescriptionELR510444 is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM; not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines.
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In Vitro——
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In Vivo——
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SynonymsELR510444 | ELR-510444 | ELR 510444.
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorMicrotubule disruptor
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1233948-35-0
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Formula Weight368.47
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Molecular FormulaC19H16N2O2S2
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=S(C1=CC=C(C)C=C1)(NC2=CC(C3=CC=C(C#N)S3)=CC=C2C)=O
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Chemical NameN-(5-(5-cyanothiophen-2-yl)-2-methylphenyl)-4-methylbenzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Risinger AL, et al. J Pharmacol Exp Ther. 2011 Mar;336(3):652-60.
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