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Home - Products - GPCR/G Protein - 5-HT Receptor - PF-05212377

PF-05212377

CAS No. 1226793-34-5

PF-05212377( SAM-760 | PF 5212377 )

Catalog No. M10869 CAS No. 1226793-34-5

PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PF-05212377
  • Note
    Research use only, not for human use.
  • Brief Description
    PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.
  • Description
    PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.Alzheimer Disease Phase 2 Clinical
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    SAM-760 | PF 5212377
  • Pathway
    GPCR/G Protein
  • Target
    5-HT Receptor
  • Recptor
    5-HT Receptor
  • Research Area
    Neurological Disease
  • Indication
    Alzheimer Disease

Chemical Information

  • CAS Number
    1226793-34-5
  • Formula Weight
    356.444
  • Molecular Formula
    C18H20N4O2S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    2-methyl-1-(phenylsulfonyl)-4-(piperazin-1-yl)-1H-benzo[d]imidazole

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38. 2. Fullerton T, et al. Alzheimers Res Ther. 2018 Apr 5;10(1):38.
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