CCX-777

CAS No. 1226686-36-7

CCX-777( CCX 777 | CCX777 )

Catalog No. M10867 CAS No. 1226686-36-7

A small-molecule partial agonist of CXCR7 (ACKR3).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 336 In Stock
50MG 1782 In Stock
100MG 2250 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CCX-777
  • Note
    Research use only, not for human use.
  • Brief Description
    A small-molecule partial agonist of CXCR7 (ACKR3).
  • Description
    A small-molecule partial agonist of CXCR7 (ACKR3).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CCX 777 | CCX777
  • Pathway
    GPCR/G Protein
  • Target
    Chemokine Receptor
  • Recptor
    Chemokine Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1226686-36-7
  • Formula Weight
    593.791
  • Molecular Formula
    C31H43N7O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (84.21 mM)
  • SMILES
    O=C(NCCN1CCCC1)CC(N2CCN(C3=C4N=CC=CC4=CC=C3OC)CCC2)C5=CSC(N6CCOCC6)=N5
  • Chemical Name
    3-(4-(7-methoxyquinolin-8-yl)-1,4-diazepan-1-yl)-3-(2-morpholinothiazol-4-yl)-N-(2-(pyrrolidin-1-yl)ethyl)propanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gustavsson M, et al. Nat Commun. 2017 Jan 18;8:14135. 2. Zabel BA, et al. J Immunol. 2009 Sep 1;183(5):3204-11.
molnova catalog
related products
  • AZ084

    AZ084 (AZ-084) is a potent, selective, allosteric, orally available CCR8 antagonist with Ki of 0.9 nM.

  • ML 604086

    ML 604086 (ML604086) is a potent, selective CCR8 inhibitor that inhibits CCL1 mediated chemotaxis and increases in intracellular Ca2+ concentrations with IC50 of 1.3?uM and 1.0?uM respectively in cellular assays.

  • C-021

    C-021 is a potent and orally bioavailable CCR4 antagonist with IC50 of 0.14 uM and 0.039 uM for inhibition of chemotaxis in human and mouse, respectively.