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GLPG-0492
CAS No. 1215085-92-9
GLPG-0492( GLPG0492 )
Catalog No. M10803 CAS No. 1215085-92-9
A novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 169 | In Stock |
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| 5MG | 159 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 377 | In Stock |
|
| 50MG | 532 | In Stock |
|
| 100MG | 714 | In Stock |
|
| 200MG | 918 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGLPG-0492
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NoteResearch use only, not for human use.
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Brief DescriptionA novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM.
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DescriptionA novel, orally active, non-steroidal selective androgen receptor modulator (SARM) with in vitro potency of 13 nM; exhibits anabolic activity on muscle, strongly dissociated from the androgenic activity on prostate in a classical model of orchidectomized rat; shows a potential treatment for Duchenne muscular dystrophy (DMD).Other Indication Phase 1 Clinical.
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In Vitro——
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In Vivo——
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SynonymsGLPG0492
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PathwayEndocrinology/Hormones
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TargetAndrogen Receptor (AR)
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RecptorAndrogen Receptor (AR)
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Research AreaOther Indications
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IndicationOther Disease
Chemical Information
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CAS Number1215085-92-9
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Formula Weight389.328
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Molecular FormulaC19H14F3N3O3
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESN#CC1=CC=C(N(C(N(C)[C@]2(CO)C3=CC=CC=C3)=O)C2=O)C=C1C(F)(F)F
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Chemical NameBenzonitrile, 4-[(4S)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Nique F, et al. J Med Chem. 2012 Oct 11;55(19):8236-47.
2. Cozzoli A, et al. Pharmacol Res. 2013 Jun;72:9-24.
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