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Solcitinib
CAS No. 1206163-45-2
Solcitinib( GSK-2586184 | GLPG-0778 )
Catalog No. M10753 CAS No. 1206163-45-2
A potent, selective JAK1 inhibitor for the treatment of psoriasis, lupus, and ulcerative colitis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 49 | In Stock |
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| 25MG | 87 | In Stock |
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| 50MG | 111 | In Stock |
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| 100MG | 183 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSolcitinib
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective JAK1 inhibitor for the treatment of psoriasis, lupus, and ulcerative colitis.
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DescriptionA potent, selective JAK1 inhibitor for the treatment of psoriasis, lupus, and ulcerative colitis.Psoriasis Phase 2 Clinical(In Vitro):Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively. Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis.
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In VitroSolcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively. Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis.
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In Vivo——
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SynonymsGSK-2586184 | GLPG-0778
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PathwayAngiogenesis
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TargetJAK
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RecptorJAK1
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Research AreaInflammation/Immunology
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IndicationPsoriasis
Chemical Information
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CAS Number1206163-45-2
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Formula Weight389.4503
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Molecular FormulaC22H23N5O2
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Purity>98% (HPLC)
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SolubilityDMSO: 20 mg/mL
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SMILESCC1(CN(C1)C(=O)C2=CC=C(C=C2)C3=CC=CC4=NC(=NN43)NC(=O)C5CC5)C
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Chemical NameCyclopropanecarboxamide, N-[5-[4-[(3,3-dimethyl-1-azetidinyl)carbonyl]phenyl][1,2,4]triazolo[1,5-a]pyridin-2-yl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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