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AM-0561

CAS No. 1202764-63-3

AM-0561( AM0561 )

Catalog No. M10738 CAS No. 1202764-63-3

AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

AM-0561
Note

Research use only, not for human use.
Brief Description

AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.
Description

AM-0561 (AM0561) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 0.3 nM.
In Vitro

——
In Vivo

——
Synonyms

AM0561
Pathway

Apoptosis
Target

NF-κB
Recptor

NF-κB
Research Area

——
Indication

——

Chemical Information

CAS Number

1202764-63-3
Formula Weight

396.853
Molecular Formula

C18H13ClN6OS
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(C#CC1=CN2C(=NC=C2C3=NC(=NC=C3Cl)N)C=C1)(C4=NC=CS4)O
Chemical Name

(R)-4-(3-(2-amino-5-chloropyrimidin-4-yl)imidazo[1,2-a]pyridin-6-yl)-2-(thiazol-2-yl)but-3-yn-2-ol

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Demchenko YN, et al. Oncotarget. 2014 Jun 30;5(12):4554-66.

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