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UNC0224
CAS No. 1197196-48-7
UNC0224( UNC 0224 | UNC-0224 )
Catalog No. M10700 CAS No. 1197196-48-7
A potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 60 | In Stock |
|
| 5MG | 88 | In Stock |
|
| 10MG | 146 | In Stock |
|
| 25MG | 336 | In Stock |
|
| 50MG | 529 | In Stock |
|
| 100MG | 754 | In Stock |
|
| 500MG | 1548 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameUNC0224
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays.
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DescriptionA potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays; dispalys >1000-fold selectivity for G9a over SET7/9, SET8, PRMT3 and JMJD2E (IC50>4 uM).
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In Vitro——
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In Vivo——
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SynonymsUNC 0224 | UNC-0224
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorHMTase
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Research AreaOther Indications
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Indication——
Chemical Information
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CAS Number1197196-48-7
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Formula Weight485.6653
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Molecular FormulaC26H43N7O2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCN1CCC(NC2=C3C=C(OC)C(OCCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1
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Chemical Name4-Quinazolinamine, 7-[3-(dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Liu F, et al. J Med Chem. 2010 Aug 12;53(15):5844-57.
2. Liu F, et al. J Med Chem. 2009 Dec 24;52(24):7950-3.
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