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Oxacillin sodium

CAS No. 1173-88-2

Oxacillin sodium( Micropenin | NSC 527712 | SQ16423 )

Catalog No. M10585 CAS No. 1173-88-2

Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Oxacillin sodium
  • Note
    Research use only, not for human use.
  • Brief Description
    Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.
  • Description
    Oxacillin sodium salt is a narrow-spectrum β-lactam antibiotic of the penicillin class.(In Vitro):Oxacillin inhibits gram positive pathogens with MICs of 0.05, 0.09, 0.32 and 0.80 μg/mL against group A streptococci, Pneutnococci, susceptible staphylococci and penicillin-resistant staphylococci, respectively.The Oxacillin-resistant strains are highly resistant to other penicillins.(In Vivo):Oxacillin (50-800 mg/kg; s.c.; once) shows curative dose (CD50) of 253.3 mg/kg in mice infected with Staphylococcus aureus Evans. The oral CD50 of Oxacillin is 187.2 mg/kg.
  • In Vitro
    Oxacillin inhibits gram positive pathogens with MICs of 0.05, 0.09, 0.32 and 0.80 μg/mL against group A streptococci, Pneutnococci, susceptible staphylococci and penicillin-resistant staphylococci, respectively.The Oxacillin-resistant strains are highly resistant to other penicillins.
  • In Vivo
    Oxacillin (50-800 mg/kg; s.c.; once) shows curative dose (CD50) of 253.3 mg/kg in mice infected with Staphylococcus aureus Evans. The oral CD50 of Oxacillin is 187.2 mg/kg. Animal Model:CD-1 strain male albino mice infected with S. aureus Evans Dosage:50, 100, 200, 400 and 800 mg/kg Administration:Subcutaneous injection, onceResult:Showed therapeutic activity with CD50 of 253.3 mg/kg.
  • Synonyms
    Micropenin | NSC 527712 | SQ16423
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    1173-88-2
  • Formula Weight
    423.43
  • Molecular Formula
    C19H18N3NaO5S
  • Purity
    >98% (HPLC)
  • Solubility
    Water: 88 mg/mL
  • SMILES
    CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)N[C@H]3[C@@H]4N(C3=O)[C@H](C(S4)(C)C)C(=O)[O-].[Na+]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Woods GL, Yam P. Antimicrob Agents ChemOthers. 1988 Nov;32(11):1614-8.
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