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AVN-211
CAS No. 1173103-84-8
AVN-211( AVN211 | CD-008-0173 )
Catalog No. M10580 CAS No. 1173103-84-8
AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameAVN-211
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NoteResearch use only, not for human use.
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Brief DescriptionAVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.
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DescriptionAVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM; shows a similar or better anxiolytic efficacy than fenobam, rufinamide, lorazepam, and buspirone in an elevated plus-maze model; significantly delayes or partially halts the progressive decline in memory function associated with AD.Schizophrenia Phase 3 Clinical.
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In Vitro——
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In Vivo——
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SynonymsAVN211 | CD-008-0173
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PathwayGPCR/G Protein
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research AreaNeurological Disease
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IndicationSchizophrenia
Chemical Information
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CAS Number1173103-84-8
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Formula Weight333.424
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Molecular FormulaC15H15N3O2S2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=C2N=C(C)C=C(C)N2N=C1SC)(C3=CC=CC=C3)=O
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Chemical Name5,7-Dimethyl-2-(methylthio)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ivachtchenko AV, et al. Mol Pharm. 2016 Mar 7;13(3):945-63.
2. Morozova MA,et al. CNS Spectr. 2014 Aug;19(4):316-23.
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