Cart
sales@molnova.com
NAN-190 hydrobromide
CAS No. 115338-32-4
NAN-190 hydrobromide( NAN190 hydrobromide | NAN 190 hydrobromide )
Catalog No. M10539 CAS No. 115338-32-4
NAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
|
| 10MG | 29 | In Stock |
|
| 25MG | 34 | In Stock |
|
| 50MG | 41 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNAN-190 hydrobromide
-
NoteResearch use only, not for human use.
-
Brief DescriptionNAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor.
-
DescriptionNAN-190 is a 5-HT1A receptor antagonist with Ki of 0.6 nM; also potently blocks the α2-adrenergic receptor; antagonizes the stimulation by norepinephrine of phosphoinositide turnover in rat cortical slices.Anxiety Preclinical
-
In Vitro——
-
In VivoNAN-190 hydrobromide (0.5 mg/kg, ip) is injected concomitantly with the effective dose of fluoxetine. NAN-190 reverses the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.
-
SynonymsNAN190 hydrobromide | NAN 190 hydrobromide
-
PathwayGPCR/G Protein
-
Target5-HT Receptor
-
Recptor5-HT Receptor
-
Research AreaNeurological Disease
-
IndicationAnxiety
Chemical Information
-
CAS Number115338-32-4
-
Formula Weight474.3907
-
Molecular FormulaC23H28BrN3O3
-
Purity>98% (HPLC)
-
SolubilityDMSO: 36.23 mg/mL
-
SMILESCOC1=CC=CC=C1N2CCN(CC2)CCCCN3C(=O)C4=CC=CC=C4C3=O.Br
-
Chemical Name1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-, hydrobromide (1:1)
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Claustre Y, et al. Eur J Pharmacol. 1991 Oct 29;204(1):71-7.
2. Zhang J, et al. J Neurosci. 2010 Feb 17;30(7):2433-41.
3. Glennon RA, et al. J Med Chem. 1988 Oct;31(10):1968-71.
molnova catalog
related products
-
Spiroxatrine
Spiroxatrine (R 5188) is a selective and potent 5-HT1α and α2-adrenergic dual antagonist with sedative activity, and inhibitory effects on 5-HT1α, 5-HT1β, 5-HT2, and dopamine receptors.
-
WAY-100635 maleate (...
WAY-100635 is a potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
-
CI 169369
CI 169369 is a selective 5-HT2 receptor antagonist used in the study of anxiety and depression.
