Cart
sales@molnova.com
LB-205
CAS No. 1113025-86-7
LB-205( LB 205 | LB205 )
Catalog No. M10416 CAS No. 1113025-86-7
A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameLB-205
-
NoteResearch use only, not for human use.
-
Brief DescriptionA Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
-
DescriptionA Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo; significantly enhances the migration of astrocytes and accelerates wound repair more effectively than SAHA and VPA; up-regulates the expression of NGF, phospho-TrkA, p-AKT, NF-κB, and Bcl-2, while down-regulates the expression of p75 NTR, phospho-JNK, and Bax.
-
In Vitro——
-
In Vivo——
-
SynonymsLB 205 | LB205
-
PathwayCell Cycle/DNA Damage
-
TargetHDAC
-
RecptorHDAC
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1113025-86-7
-
Formula Weight343.445
-
Molecular FormulaC18H21N3O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NCCCCCC(NC1=CC=CC=C1)=O)C2=CC=CC=C2S
-
Chemical Name2-mercapto-N-(6-oxo-6-(pyridin-3-ylamino)hexyl)benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lu J, et al. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5.
2. Lu J, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52.
molnova catalog
related products
-
1-Naphthohydroxamic ...
1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM).
-
CAY-10603
A highly potent and selective HDAC6 inhibitor with IC50 of 2 pM.
-
MPT0E028
MPT0E028 (MPT 0E028) is a potent HDAC inhibitor that inhibits nuclear HDAC activity with IC50 of 11.1 nM in HeLa cells.
