Cart
sales@molnova.com
PF-04531083
CAS No. 1079400-07-9
PF-04531083( PF-4531083 )
Catalog No. M10319 CAS No. 1079400-07-9
PF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 85 | In Stock |
|
| 5MG | 76 | In Stock |
|
| 10MG | 140 | In Stock |
|
| 25MG | 217 | In Stock |
|
| 50MG | 323 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePF-04531083
-
NoteResearch use only, not for human use.
-
Brief DescriptionPF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain.
-
DescriptionPF-04531083 (PF 4531083) is a potent and selective, orally available sodium channel Nav1.8 blocker for treatment of pain. Pain Phase 2 Discontinued.
-
In Vitro——
-
In Vivo——
-
SynonymsPF-4531083
-
PathwayMembrane Transporter/Ion Channel
-
TargetSodium Channel
-
RecptorSodium Channel
-
Research AreaNeurological Disease
-
IndicationPain
Chemical Information
-
CAS Number1079400-07-9
-
Formula Weight357.798
-
Molecular FormulaC17H16ClN5O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (279.49 mM)
-
SMILESCN1C(=CC=N1)C(=O)NC2=NC(=C(C=C2)C3=C(C=CC(=C3)OC)Cl)N
-
Chemical NameN-[6-amino-5-(2-chloro-5-methoxyphenyl)pyridin-2-yl]-2-methylpyrazole-3-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
molnova catalog
related products
-
GNE-131
GNE-131 is a potent and specific inhibitor of human sodium channel NaV1.7 (IC50: 3 nM).
-
E 0747
E 0747 (E0747) is a new antiarrhythmic compound that inhibits arrhythmias by inhibiting Na channels in cardiac cells.
-
Phenytoin sodium
Phenytoin sodium is an inactive voltage-gated sodium channel stabilizer.
