Home - Products - Endocrinology/Hormones - 5-HT Receptor - PF-03246799

PF-03246799

CAS No. 1065110-62-4

PF-03246799( PF 03246799 | PF03246799 | PF-3246799 )

Catalog No. M10282 CAS No. 1065110-62-4

A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
50MG	1782	Get Quote
100MG	2250	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

PF-03246799
Note

Research use only, not for human use.
Brief Description

A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.
Description

A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A; has minimal activation at either the 5-HT(2A) or 5-HT(2B) receptors, demonstrates robust efficacy in preclinical canine model of stress urinary incontinence (SUI) and attractive pharmacokinetic and safety properties.
In Vitro

——
In Vivo

——
Synonyms

PF 03246799 | PF03246799 | PF-3246799
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1065110-62-4
Formula Weight

239.322
Molecular Formula

C15H17N3
Purity

>98% (HPLC)
Solubility

——
SMILES

C12=NC(CC3=CC=CC=C3)=NC=C1CCNCC2
Chemical Name

2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Andrews MD, et al. Bioorg Med Chem Lett. 2011 May 1;21(9):2715-20. 2. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Targocil

Targocil is used as a bacteriostatic inhibitor of wall teichoic acid (WTA) biosynthesis which can inhibit the growth of methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) (MIC90s: 2 μg/ mL) for both MRSA and MSSA.
Incensole

Incensole has a protective or stimulating effect on β-cells of the rat pancreas, it also can increase the insulin secretion, which evidenced by a significant increase both in body weight and in liver glycogen.
Tetrahydroberberine

Tetrahydroberberine is an isoquinoline alkaloid isolated from corydalis tuber.

Sign In Join Free