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GAT-211
CAS No. 102704-40-5
GAT-211( GAT211 )
Catalog No. M10132 CAS No. 102704-40-5
GAT-211 (GAT211) is a selective cannabinoid 1 receptor (CB1R) positive allosteric modulator with pKb of 7.26, Arrestin2 EC50 of 775 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 92 | In Stock |
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| 25MG | 151 | In Stock |
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| 50MG | 217 | In Stock |
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| 100MG | 321 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 775 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGAT-211
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NoteResearch use only, not for human use.
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Brief DescriptionGAT-211 (GAT211) is a selective cannabinoid 1 receptor (CB1R) positive allosteric modulator with pKb of 7.26, Arrestin2 EC50 of 775 nM.
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DescriptionGAT-211 (GAT211) is a selective cannabinoid 1 receptor (CB1R) positive allosteric modulator with pKb of 7.26, Arrestin2 EC50 of 775 nM; engages CB1R allosteric site(s), enhances the binding of the orthosteric full agonist [3H]CP55,490, and reduces the binding of the orthosteric antagonist/inverse agonist [3H]SR141716A; displayed both PAM and agonist activity in HEK293A and Neuro2a cells expressing human recombinant CB1R (hCB1R) and in mouse-brain membranes rich in native CB1R.
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In Vitro——
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In Vivo——
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SynonymsGAT211
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PathwayGPCR/G Protein
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TargetCannabinoid Receptor
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RecptorCannabinoid Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number102704-40-5
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Formula Weight342.4
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Molecular FormulaC22H18N2O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (292.06 mM)
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SMILESO=[N+](CC(C1=C(C2=CC=CC=C2)NC3=C1C=CC=C3)C4=CC=CC=C4)[O-]
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Chemical Name3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Laprairie RB, et al. ACS Chem Neurosci. 2017 Jun 21;8(6):1188-1203.
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