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MV1
CAS No. 1001600-54-9
MV1( MV 1 )
Catalog No. M10018 CAS No. 1001600-54-9
A small-molecule IAP antagonist that binds to select baculovirus IAP repeat (BIR) domains resulting in dramatic induction of auto-ubiquitination activity and rapid proteasomal degradation of c-IAPs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 84 | Get Quote |
|
| 5MG | 140 | Get Quote |
|
| 10MG | 260 | Get Quote |
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| 25MG | 461 | Get Quote |
|
| 50MG | 669 | Get Quote |
|
| 100MG | 945 | Get Quote |
|
| 500MG | 1782 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMV1
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NoteResearch use only, not for human use.
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Brief DescriptionA small-molecule IAP antagonist that binds to select baculovirus IAP repeat (BIR) domains resulting in dramatic induction of auto-ubiquitination activity and rapid proteasomal degradation of c-IAPs.
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DescriptionA small-molecule IAP antagonist that binds to select baculovirus IAP repeat (BIR) domains resulting in dramatic induction of auto-ubiquitination activity and rapid proteasomal degradation of c-IAPs; induces cell death that is dependent on TNF signaling and de novo protein biosynthesis.
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In Vitro——
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In Vivo——
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SynonymsMV 1
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PathwayApoptosis
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TargetIAP
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RecptorIAP
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Research Area——
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Indication——
Chemical Information
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CAS Number1001600-54-9
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Formula Weight576.738
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Molecular FormulaC33H44N4O5
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 125 mg/mL 216.74 mM
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SMILESO=C(OC)C(NC([C@H]1N(C([C@H](C2CCCCC2)NC([C@@H](NC)C)=O)=O)CCC1)=O)C(C3=CC=CC=C3)C4=CC=CC=C4
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Chemical Namemethyl 2-((S)-1-((S)-2-cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-3,3-diphenylpropanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Varfolomeev E, et al. Cell. 2007 Nov 16;131(4):669-81.
2. Shibata N, et al. J Med Chem. 2017 Jun 23. doi: 10.1021/acs.jmedchem.7b00168.
molnova catalog
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