Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Other Targets - Lotilaner

Lotilaner

CAS No. 1369852-71-0

Lotilaner( —— )

Catalog No. M23521 CAS No. 1369852-71-0

Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 110 In Stock
5MG 178 In Stock
10MG 295 In Stock
25MG 560 In Stock
50MG 860 In Stock
100MG 1251 In Stock
200MG 1692 In Stock
500MG 2547 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Lotilaner
  • Note
    Research use only, not for human use.
  • Brief Description
    Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors.
  • Description
    Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Other Targets
  • Recptor
    GABA|Parasite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1369852-71-0
  • Formula Weight
    596.76
  • Molecular Formula
    C20H14Cl3F6N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 150 mg/mL (251.36 mM)
  • SMILES
    Cc1c(C(NCC(NCC(F)(F)F)=O)=O)sc(C(C2)=NO[C@]2(C(F)(F)F)c(cc2Cl)cc(Cl)c2Cl)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lotilaner, et al. The novel isoxazoline ectoparasiticide lotilaner (Credelio?): a non-competitive antagonist specific to invertebrates γ-aminobutyric acid-gated chloride channels (GABACls). Parasit Vectors. 2017 Nov 1;10(1):530.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Zolpidem tartrate

    Zolpidem is a prescription medication used for the treatment of insomnia, as well as some brain disorders.

  • Etomidate hydrochlor...

    Etomidate hydrochloride is a potent agonist of GABAA receptor. It is a neurological drug and effective parenteral medication and has the potential for management of endogenous hypercortisolaemia.

  • Clomethiazole

    Clomethiazole is an orally active GABAA?agonist and it is an anticonvulsant agent.

Sign In Join Free