Lorpucitinib( —— )

Catalog No. M35614 CAS No. 2230282-02-5

Lorpucitinib (JNJ-64251330) is an orally available, selective and potent JAK kinase inhibitor for the study of inflammatory and gastrointestinal disorders associated with Janus kinase (JAK) signaling.

Purity : >98% (HPLC)

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Biological Information

Product Name

Lorpucitinib
Note

Research use only, not for human use.
Brief Description

Lorpucitinib (JNJ-64251330) is an orally available, selective and potent JAK kinase inhibitor for the study of inflammatory and gastrointestinal disorders associated with Janus kinase (JAK) signaling.
Description

Lorpucitinib is a Gut-Restricted JAK Inhibitor for the research of Inflammatory Bowel Disease.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

JAK
Recptor

JAK
Research Area

——
Indication

——

Chemical Information

CAS Number

2230282-02-5
Formula Weight

408.5
Molecular Formula

C22H28N6O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (612.00 mM; Ultrasonic )
SMILES

CC(C)(O)CNC(=O)Cc1nc2cnc3[nH]ccc3c2n1[C@H]1CC[C@H](CC#N)CC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Leonard KA, Madge LA, Krawczuk PJ, Wang A, Kreutter KD, Bacani GM, Chai W, Smith RC, Tichenor MS, Harris MC, Malaviya R, Seierstad M, Johnson ME, Venable JD, Kim S, Hirst GC, Mathur AS, Rao TS, Edwards JP, Rizzolio MC, Koudriakova T. Discovery of a Gut-Re?

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