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Letolizumab
CAS No. 1450981-87-9
Letolizumab( —— )
Catalog No. M36807 CAS No. 1450981-87-9
Letolizumab (BMS-986004) is a dimeric antibody targeting CD40L for the expression of mutant IgG1 that lacks effector functions including Fc binding and complement binding.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 257 | Get Quote |
|
| 5MG | 426 | Get Quote |
|
| 10MG | 679 | Get Quote |
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| 25MG | 994 | Get Quote |
|
| 50MG | 1343 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLetolizumab
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NoteResearch use only, not for human use.
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Brief DescriptionLetolizumab (BMS-986004) is a dimeric antibody targeting CD40L for the expression of mutant IgG1 that lacks effector functions including Fc binding and complement binding.
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DescriptionLetolizumab (BMS-986004) is a monoclonal antibody targeting CD40L, which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time.
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In Vitro——
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In VivoAnimal Model:Rhesus macaques after renal transplantation.Dosage:2, 10 and 20 mg/kg.Administration:Intravenous injection; once a week for 10 weeks.Result:Increased the survival time.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorImmunology/Inflammation related
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Research Area——
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Indication——
Chemical Information
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CAS Number1450981-87-9
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Formula Weight
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Karnell JL, et al. Targeting the CD40-CD40L pathway in autoimmune diseases: Humoral immunity and beyond. Adv Drug Deliv Rev. 2019 Feb 15;141:92-103. ?
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