Laudanosine( DL-LAUDANOSINE )

Catalog No. M21227 CAS No. 1699-51-0

Laudanosine is a recognized metabolite of atracurium and cisatracurium.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Laudanosine
Note

Research use only, not for human use.
Brief Description

Laudanosine is a recognized metabolite of atracurium and cisatracurium.
Description

Laudanosine is a recognized metabolite of atracurium and cisatracurium.
In Vitro

——
In Vivo

DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses. Animal Model:Male CFLP mice weighing 18-25 g, and male Wistar rats weighing 120-150 g .Dosage:10-20 mg/kg.Administration:IV.Result:Caused convulsions and hind limb extensions.
Synonyms

DL-LAUDANOSINE
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

1699-51-0
Formula Weight

357.4
Molecular Formula

C21H27NO4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (279.77 mM)
SMILES

CN(CCc1c2)C(Cc(cc3)cc(OC)c3OC)c1cc(OC)c2OC
Chemical Name

1-(34-dimethoxybenzyl)-67-dimethoxy-2-methyl-1234-tetrahydroisoquinoline

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Shi W Z Fahey M R Fisher D M et al. Laudanosine (A Metabolite of Atracurium) Increases the Minimum Alveolar Concentration of Halothane in Rabbits[J]. Anesthesiology 1985 63(6):584-588.

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