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Lapachol

CAS No. 84-79-7

Lapachol( Lapachol | NSC-11905 | Tecomin | Bethabarra wood )

Catalog No. M19177 CAS No. 84-79-7

Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Lapachol
  • Note
    Research use only, not for human use.
  • Brief Description
    Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties.
  • Description
    Lapachol has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
  • In Vitro
    Cell Proliferation Assay Cell Line:Murine CD4 T cells Concentration:10, 30, 100 μM Incubation Time:4 days Result:Inhibited the proliferation of murine CD4 T cells in a dose-dependent manner.
  • In Vivo
    Animal Model:Male DBA1/J mice (10-12 weeks old) with collagen-induced arthritis (CIA) modelsDosage:3 mg/kg and 10 mg/kg Administration:Orally; once a day for 4 weeks Result:Markedly attenuated the severity of arthritis in CIA mice at both doses. Markedly reduced all histopathological features of arthritis severity.
  • Synonyms
    Lapachol | NSC-11905 | Tecomin | Bethabarra wood
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    others
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    84-79-7
  • Formula Weight
    242.27
  • Molecular Formula
    C15H14O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 66.67 mg/mL (275.19 mM)
  • SMILES
    CC(C)=CCC1=C(O)C(=O)c2ccccc2C1=O
  • Chemical Name
    2-hydroxy-3-(3-methylbut-2-en-1-yl)naphthalene-1,4-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Costa WF,et al. Lapachol as an epithelial tumor inhibitor agent in Drosophila melanogaster heterozygote for tumor suppressor gene wts.Genet Mol Res. 2011 Dec 22;10(4):3236-45.
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