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Lactisole
CAS No. 150436-68-3
Lactisole( 2-(4-Methoxyphenoxy)propanoic acid )
Catalog No. M28055 CAS No. 150436-68-3
Lactisole is an inhibitor of the glucose-sensing receptor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 32 | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLactisole
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NoteResearch use only, not for human use.
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Brief DescriptionLactisole is an inhibitor of the glucose-sensing receptor.
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DescriptionLactisole is an inhibitor of the glucose-sensing receptor.(In Vitro):In MIN6 cells, in a dose-dependent manner, lactisole inhibited insulin secretion induced by sweeteners, acesulfame-K, sucralose and glycyrrhizin. The IC50 was ～4 mmol/l. Lactisole attenuated the elevation of cytoplasmic Ca2+ concentration ([Ca2+]c) evoked by sucralose and acesulfame-K but did not affect the elevation of intracellular cAMP concentration ([cAMP]c) induced by these sweeteners. Lactisole also inhibited the action of glucose in MIN6 cells. Thus, lactisole significantly reduced elevations of intracellular [NADH] and intracellular [ATP] induced by glucose, and also inhibited glucose-induced insulin secretion.
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In Vitro——
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In Vivo——
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Synonyms2-(4-Methoxyphenoxy)propanoic acid
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PathwayOthers
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TargetOther Targets
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RecptorApoptosis|PKG
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Research Area——
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Indication——
Chemical Information
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CAS Number150436-68-3
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Formula Weight218.184
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Molecular FormulaC10H11NaO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (572.92 mM)
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SMILES[Na+].COc1ccc(OC(C)C([O-])=O)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Singh T, et al. Nitric oxide donor exisulind is an effective inhibitor of murine photocarcinogenesis. Photochem Photobiol. 2012 Sep-Oct;88(5):1141-8.
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