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L-Methionine
CAS No. 63-68-3
L-Methionine( L-Methionin | L(-)-Methionin )
Catalog No. M19651 CAS No. 63-68-3
L-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | 43 | In Stock |
|
Biological Information
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Product NameL-Methionine
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NoteResearch use only, not for human use.
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Brief DescriptionL-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.
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DescriptionL-Methionine is the L-isomer of Methionine an essential amino acid for human development. Methionine acts as a hepatoprotectant.
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In VitroCell Proliferation Assay Cell Line:BXPC-3, HPAC Concentration:5 mg/mL Incubation Time:7 or 3 days Result:Reduced growth of BXPC-3 cells by 31 and 32%, respectively. Reduced growth of HPAC cells by 35% and 18%, respectively. Reduced S to G2 transition in BXPC-3 cells and intervened in both G1–S and S–G2 transitions in HPAC cells. Increased late cell apoptosis at a percentage of 76% in BXPC-3 cells.Western Blot Analysis Cell Line:ECV304 Concentration:0.3, 1, 3, 5, 10 mM Incubation Time:24 h Result:Increased the level of HO-1 protein up to 9.5-fold and the HO-1 activity.
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In VivoAnimal Model:Male Wistar rats (body weight 70-80 g) Dosage:215,268.8, 322.5, 430 mg/kg Administration:p.o.Result:Reduced the hepatic ROS levels and the hepatic MDA contents. Increased the hepatic T-AOC, CAT and T-SOD. Increased the hepatic activity of GCL, GR, GST and GPx.
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SynonymsL-Methionin | L(-)-Methionin
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite
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Research AreaMetabolic Disease
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IndicationNutritional fortifier acute hepatitis cirrhosis
Chemical Information
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CAS Number63-68-3
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Formula Weight149.21
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Molecular FormulaC5H11NO2S
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Purity>98% (HPLC)
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SolubilityDMSO:10uM;Water:Soluble
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SMILESCSCC[C@H](N)C(O)=O
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Chemical NameL-methionine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sreekumar A Poisson L M Rajendiran T M et al. Corrigendum: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression[J]. Nature 2009 457(7231):910-914.
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