Cart
sales@molnova.com
L-Kynurenine
CAS No. 2922-83-0
L-Kynurenine( (S)-Kynurenine )
Catalog No. M19725 CAS No. 2922-83-0
L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 38 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameL-Kynurenine
-
NoteResearch use only, not for human use.
-
Brief DescriptionL-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses.
-
DescriptionL-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
-
In Vitro——
-
In Vivo——
-
Synonyms(S)-Kynurenine
-
PathwayProteasome/Ubiquitin
-
TargetEndogenous Metabolite
-
RecptorHuman Endogenous Metabolite|AhR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2922-83-0
-
Formula Weight208.21
-
Molecular FormulaC10H12N2O3
-
Purity>98% (HPLC)
-
SolubilityDMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL
-
SMILESN[C@@H](CC(=O)c1ccccc1N)C(O)=O
-
Chemical Name(S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kolho K L Pessia A Jaakkola T et al. Faecal and serum metabolomics in paediatric inflammatory bowel disease[J]. Journal of Crohns & Colitis 2017 11(3):321-334.
molnova catalog
related products
-
N-Acetyl-L-tryptopha...
N-Acetyl-L-tryptophan?is an inhibitor of neurokinin 1 receptor (NK1-receptor, NK1R).
-
Lipoxin A4
Lipoxin A4 (LXA4) is a lipoxygenase-derived arachidonate-like mediator with anti-inflammatory properties.Lipoxin A4 attenuates MSU crystal-induced NLRP3 inflammasome activation through inhibition of Nrf2, and regulates M1/M2 macrophage polarization through the FPR2-IRF pathway.
-
Phosphorylcholine B
Phosphorylcholine is widely present in the biological world, which is a phospholipid present in the eukaryotic biofilm, and also in the symbiotic bacteria or pathogens associated with eukaryotes.
