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Kinetensin
CAS No. 103131-69-7
Kinetensin( Kinetensin (human) )
Catalog No. M29815 CAS No. 103131-69-7
Kinetensin is a neurotensin-like peptide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 133 | Get Quote |
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| 10MG | 214 | Get Quote |
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| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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Biological Information
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Product NameKinetensin
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NoteResearch use only, not for human use.
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Brief DescriptionKinetensin is a neurotensin-like peptide.
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DescriptionKinetensin is a neurotensin-like peptide.(In Vitro):The peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium.(In Vivo):Kinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats.
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In VitroThe peptide kinetensin isolated from pepsin-treated human plasma induces a dose-dependent release of histamine when exposed to rat peritoneal mast cells. The threshold concentration is around 1 μM, the ED50 is 10 μM, and the optimal concentration of between 100 to 1000 μM released 80% of the total histamine. Kinetensin is 10 to 100 times less potent than neurotensin and equipotent with the opioid peptide dynorphin. The histamine release is clearly temperature-dependent, with no release occurring at 0 or 45 °C and with an optimum around 37 °C. The histamine release is significantly reduced in the absence of extracellular calcium.
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In VivoKinetensin also induces a dose-dependent increase in vascular permeability when injected intradermally into rats.
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SynonymsKinetensin (human)
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PathwayOthers
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TargetOther Targets
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RecptorNeurotensin Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number103131-69-7
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Formula Weight1172.38
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Molecular FormulaC56H85N17O11
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (85.30 mM)
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SMILES——
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Chemical NameSequence:Ile-Ala-Arg-Arg-His-Pro-Tyr-Phe-Leu
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Mogard MH, et al. The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin. Biochem Biophys Res Commun. 1986 May 14;136(3):983-8.
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