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KL1333
CAS No. 1800405-30-4
KL1333( NQO1 activator 1 )
Catalog No. M23811 CAS No. 1800405-30-4
KL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 177 | In Stock |
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| 5MG | 259 | In Stock |
|
| 10MG | 404 | In Stock |
|
| 25MG | 665 | In Stock |
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| 50MG | 888 | In Stock |
|
| 100MG | 1251 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameKL1333
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NoteResearch use only, not for human use.
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Brief DescriptionKL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts.
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DescriptionKL1333 enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H: NQO1 as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation.
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In Vitro——
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In Vivo——
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SynonymsNQO1 activator 1
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PathwayMembrane Transporter/Ion Channel
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TargetNADPH
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RecptorNQO1
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Research Area——
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Indication——
Chemical Information
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CAS Number1800405-30-4
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Formula Weight240.26
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Molecular FormulaC14H12N2O2
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Purity>98% (HPLC)
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SolubilityDMSO:245 mg/mL (1019.73 mM; Need ultrasonic)
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SMILESCC(C)c1nc(-c(cccc2)c2C(C2=O)=O)c2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Seo KS, et al. KL1333, a Novel NAD+ Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts. Front Neurol. 2018 Jul 5;9:552.
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