KAN0438757

CAS No. 1451255-59-6

KAN0438757( —— )

Catalog No. M23618 CAS No. 1451255-59-6

KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 182 In Stock
10MG 291 In Stock
25MG 525 In Stock
50MG 721 In Stock
100MG 981 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    KAN0438757
  • Note
    Research use only, not for human use.
  • Brief Description
    KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
  • Description
    KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Glucokinase
  • Recptor
    PFKFB3
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1451255-59-6
  • Formula Weight
    447.43
  • Molecular Formula
    C21H18FNO7S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:130 mg/mL (290.55 mM; Need ultrasonic)
  • SMILES
    C1=CC(=CC(=C1)S(=O)(=O)NC2=CC(=C(C=C2)C(=O)OCCO)O)C3=C(C=CC(=C3)F)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872.
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