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JAK3i
CAS No. 1918238-72-8
JAK3i( JAK3 inhibitor JAK3i )
Catalog No. M13007 CAS No. 1918238-72-8
JAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 745 | Get Quote |
|
| 10MG | 1017 | Get Quote |
|
| 25MG | 1431 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameJAK3i
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NoteResearch use only, not for human use.
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Brief DescriptionJAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM.
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DescriptionJAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM, shows high selectivity (>3,000-fold) against the closely related kinase domains in JAK1, JAK2, or TYK2, displays 1,300-fold, 600-fold, and 50-fold over EGFR, ITK, and BTK respectively.
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In Vitro——
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In Vivo——
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SynonymsJAK3 inhibitor JAK3i
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PathwayAngiogenesis
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TargetJAK
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RecptorJAK
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Research Area——
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Indication——
Chemical Information
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CAS Number1918238-72-8
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Formula Weight354.34
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Molecular FormulaC18H15FN4O3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CNC2=NC=NC(C3=CC(NC(C=C)=O)=CC=C3F)=C21)OCC
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Chemical NameEthyl 4-(5-acrylamido-2-fluorophenyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Smith GA, et al. Nat Chem Biol. 2016 May;12(5):373-9.
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