Cart
sales@molnova.com
Itaconate-alkyne
CAS No. 2454181-83-8
Itaconate-alkyne( ITalk )
Catalog No. M28361 CAS No. 2454181-83-8
Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 147 | Get Quote |
|
| 10MG | 237 | Get Quote |
|
| 25MG | 484 | Get Quote |
|
| 50MG | 700 | Get Quote |
|
| 100MG | 981 | Get Quote |
|
| 500MG | 1962 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameItaconate-alkyne
-
NoteResearch use only, not for human use.
-
Brief DescriptionItaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.
-
DescriptionItaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.(In Vitro):Itaconate-alkyne can capture itaconate targets including DNA damage-binding protein 1 (DDB1), Gelsolin (GSN), ATP-citrate synthase (ACLY) and Adenylate kinase 2 (AK2) in inflammatory macrophages.
-
In Vitro——
-
In Vivo——
-
SynonymsITalk
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2454181-83-8
-
Formula Weight238.28
-
Molecular FormulaC13H18O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 250 mg/mL (1049.19 mM)
-
SMILESO=C(O)C(=C)CC(=O)OCCCCCCC#C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Daly JW, et al. Structure-activity relationships for N6-substituted adenosines at a brain A1-adenosine receptor with a comparison to an A2-adenosine receptor regulating coronary blood flow. Biochem Pharmacol. 1986 Aug 1;35(15):2467-81.
molnova catalog
related products
-
SW2_110A
SW2_110A is a cell-permeable, selective chromosome group 8 chromosome domain (CBX8 ChD) inhibitor with a Kd of 800 nM.
-
Arsenic oxide
Arsenic trioxide is a chemOthersaputic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents.
-
EED226
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.
