ISRIB-A15

CAS No. 1628478-12-5

ISRIB-A15( —— )

Catalog No. M35963 CAS No. 1628478-12-5

ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 62 Get Quote
5MG 92 Get Quote
10MG 151 Get Quote
25MG 235 Get Quote
50MG 380 Get Quote
100MG 556 Get Quote
500MG 1197 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    ISRIB-A15
  • Note
    Research use only, not for human use.
  • Brief Description
    ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
  • Description
    ISR-IN-2 (Compound 47) is an inhibitor of the integrated stress response (EC50: 0.8 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1628478-12-5
  • Formula Weight
    520.23
  • Molecular Formula
    C22H22Cl4N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 2.5 mg/mL (4.81 mM; Ultrasonic (<60°C)
  • SMILES
    Clc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)c(Cl)c2)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. ?
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