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IN-1233
CAS No. 1093952-95-4
IN-1233( IN1233 | IN 1233 )
Catalog No. M10361 CAS No. 1093952-95-4
A potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameIN-1233
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM.
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DescriptionA potent and selective TGF-βRI (ALK5) inhibitor with IC50 of 34 nM, prevents tissue hyperplasia in the rat urethra or common iliac artery.
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In Vitro——
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In Vivo——
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SynonymsIN1233 | IN 1233
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PathwayTGF-beta/Smad
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TargetTGFBR
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RecptorTGFBR
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Research Area——
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Indication——
Chemical Information
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CAS Number1093952-95-4
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Formula Weight419.488
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Molecular FormulaC26H21N5O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name3-((4-(6-methylpyridin-2-yl)-5-(quinolin-6-yl)-1H-imidazol-2-yl)methyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kim JH, et al. Radiology, May 2013 Volume 267, Issue 2, doi.org/10.1148/radiol.121203612. Kim JH, et al. Radiology. 2010 Apr;255(1):75-82.
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