IBMX

CAS No. 28822-58-4

IBMX( Isobutylmethylxanthine | 1-Methyl-3-Isobutylxanthine )

Catalog No. M13880 CAS No. 28822-58-4

3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 42 In Stock
100MG 52 In Stock
200MG 95 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    IBMX
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor.
  • Description
    3-Isobutyl-1-methylxanthine is a potent cyclic nucleotide phosphodiesterase inhibitor; due to this action, the compound increases cyclic AMP and cyclic GMP in tissue and thereby activates cyclic nucleotide regulated protein kinases.(In Vitro):IBMX (0.5 mM) induces neural-like cells for neural differentiation of cord blood derived mesenchymal-like stem cells.IBMX induces initiation of the differentiation of programpre-adipocytes.IBMX (500 μM) induces neuronal differentiation of small cell lung cancer.IBMX (100 μM) induces differentiation of 3T3-LI adipocytes.IBMX (500 μM) induces adipose tissue-derived stem cells (ADSC) differentiate into neuron-like cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Isobutylmethylxanthine | 1-Methyl-3-Isobutylxanthine
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE3| PDE4| PDE5
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    28822-58-4
  • Formula Weight
    222.24
  • Molecular Formula
    C10H14N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    Soluble in DMSO
  • SMILES
    O=C(N1C)N(CC(C)C)C2=C(NC=N2)C1=O
  • Chemical Name
    3-Isobutyl-1-methylxanthine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jin KS, et al. Food Chem Toxicol. 2014 Jun;68:38-43.
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