I-152( —— )

Catalog No. M36625 CAS No. 311343-11-0

I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	119	Get Quote
5MG	200	Get Quote
10MG	342	Get Quote
25MG	569	Get Quote
50MG	914	Get Quote
100MG	1431	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

I-152
Note

Research use only, not for human use.
Brief Description

I-152, a conjugate of N-acetyl-cysteine (NAC) and cysteamine (MEA), activates NRF2 and ATF4 signaling pathways and exhibits anti-proliferative properties .
Description

I-152 is a conjugate containing N-acetyl-cysteine (NAC) and cysteamine (MEA). I-152 activates NRF2 and ATF4 signals. I-152 has anti-proliferative properties.
In Vitro

Western Blot Analysis Cell Line:RAW 264.7 cells.Concentration:0.062, 0.125, 0.25, 1, 5 or 10 mM.Incubation Time:2 h or 24 h.Result:Reduced the expression of NRF2/β-ACTIN, increased the expression of GCLM.
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

311343-11-0
Formula Weight

264.36
Molecular Formula

C9H16N2O3S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (378.27 mM; Ultrasonic )
SMILES

[C@H](C(NCCSC(C)=O)=O)(NC(C)=O)CS
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Crinelli R, et al. Activation of NRF2 and ATF4 Signaling by the Pro-Glutathione Molecule I-152, a Co-Drug of N-Acetyl-Cysteine and Cysteamine. Antioxidants (Basel). 2021 Jan 26;10(2):175. ?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks