Hyperoside( Hyperoside | NSC 407304 | Quercetin-3-O-galactoside )

Catalog No. M14615 CAS No. 482-36-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Hyperoside
Note

Research use only, not for human use.
Brief Description

Extracted from CLUSIACEAE fruit;Suitability:Ethanol,methanol,acetone and pyridine;Store the product in sealed,cool and dry condition.
Description

Extracted from clusiaceaefruit;Suitability:Ethanol,methanol,acetone and pyridine;Store the product in sealed,cool and dry condition.
In Vitro

Cell Viability Assay Cell Line:MCF-7 and 4T1 cellsConcentration:12.5, 25, 50, 75, or 100 μM Incubation Time:6, 12, or 24 h Result:Inhibited cell growth in a time- and concentration-dependent manner.Apoptosis Analysis Cell Line:MCF-7 and 4T1 cells Concentration:25, 50 and 100 μM Incubation Time:24 h Result:Increased the expressions of Bax, cleaved caspase-3 and cleaved PARP, and decreased Bcl-2 in mRNA and protein levels.
In Vivo

Animal Model:Balb/c mice injected with 4T1 cells Dosage:50 mg/kg Administration:Intraperitoneal injection; 50 mg/kg; every two day for 18 days Result:Reduced the average tumor volume compared to the control group.Decreased Bcl-2 and increased bax and cleaved caspase-3.
Synonyms

Hyperoside | NSC 407304 | Quercetin-3-O-galactoside
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Inflammation/Immunology
Indication

——

CAS Number

482-36-0
Formula Weight

464.38
Molecular Formula

C21H20O12
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)O)O)O
Chemical Name

——

1.Zhang N, et al. PLoS One. 2014 Jul 1;9(7):e98973.

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