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Herniarin
CAS No. 531-59-9
Herniarin( 7-Methoxycoumarin | Methyl umbelliferyl ether )
Catalog No. M18747 CAS No. 531-59-9
Herniarin is a natural coumarin with antitumor effect.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 38 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHerniarin
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NoteResearch use only, not for human use.
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Brief DescriptionHerniarin is a natural coumarin with antitumor effect.
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DescriptionHerniarin is a natural coumarin with antitumor effect.(In Vitro):Herniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
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In VitroHerniarin is cytotoxic to breast carcinoma cell line MCF-7 with an IC50 of 207.6 μM. Herniarin (100 μM) also induces apoptosis in MCF-7 cells. Herniarin alone has no obvious cytotoxicity on transitional cell carcinoma (TCC) cells, but when in combination with 5?μg/mL cisplatin, Herniarin (80 μg/mL) potently enhances the antitumor effect of cisplatin, and increases chromatin condensation.
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In Vivo——
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Synonyms7-Methoxycoumarin | Methyl umbelliferyl ether
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number531-59-9
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Formula Weight176.17
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Molecular FormulaC10H8O3
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Purity>98% (HPLC)
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SolubilityDMSO : ≥ 125 mg/mL; 709.54 mM
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SMILESCOc1ccc2ccc(=O)oc2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mousavi SH, et al. Comparative analysis of the cytotoxic effect of 7-prenyloxycoumarin compounds and herniarin on MCF-7 cell line. Avicenna J Phytomed. 2015 Nov-Dec;5(6):520-30.
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