Hematin

Research use only, not for human use.

Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.

Hematin is an iron-containing porphyrin. It is used for testing in vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.

Hematin (0.01 mg/ml) inhibits the clotting of bovine fibrinogen (1.3 to 2.6 mg/ml) by bovine thrombin (0.12 U/ml) and inhibits the hydrolysis of a synthetic substrate by human thrombin.Hematin (0.035 mg/ml) reduces VIII:C activity from 0.88 to 0.40 U/ml.Hematin (0.05 mg/ml) inhibits the activation of VIII:C by thrombin (0.04 U/ml).Hematin (0.09 mg/ml) inhibits the hydrolysis of a synthetic substrate by plasmin.

Hematin (i.v.; single injection) suppressed porphyrin production in SD rat (weighing 160-205 g).

Ferrihemate | Ferriheme | Ferriheme hydroxide | Ferrihemic acid

Others

Other Targets

Antifection| VEGFR

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15489-90-4

633.5

C34H33FeN4O5

>98% (HPLC)

In Vitro:?DMSO : 1.43 mg/mL (2.26 mM)

CC1=C(C=C2C(C)=C(C=C)C3=[N]2[Fe]45(O)N6C(C(C)=C(C=C)C6=C7)=C3)N4C(C=C8[N]5=C7C(C)=C8CCC(O)=O)=C1CCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years