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HM43239
CAS No. 2569527-64-4
HM43239( —— )
Catalog No. M28680 CAS No. 2569527-64-4
HM43239 is a selective FLT3 inhibitor (IC50s: 1.1 nM for FLT3 WT, 1.8 nM for FLT3 ITD, and 1.0 nM for FLT3 D835Y kinases, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 144 | Get Quote |
|
| 10MG | 222 | Get Quote |
|
| 25MG | 421 | Get Quote |
|
| 50MG | 631 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameHM43239
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NoteResearch use only, not for human use.
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Brief DescriptionHM43239 is a selective FLT3 inhibitor (IC50s: 1.1 nM for FLT3 WT, 1.8 nM for FLT3 ITD, and 1.0 nM for FLT3 D835Y kinases, respectively).
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DescriptionHM43239 is a selective FLT3 inhibitor (IC50s: 1.1 nM for FLT3 WT, 1.8 nM for FLT3 ITD, and 1.0 nM for FLT3 D835Y kinases, respectively).(In Vivo):Mesdopetam (3.7, 11, 33, or 100 μmol/kg; s.c.) dose-dependently inhibits the behavioral activation following pretreatment with D-amphetamine or MK-80 . Mesdopetam (10 mg/kg; i.p.; fourteen-week-old male C57BL/J mice) promotes a sedative effect similar to haloperidol with significantly reduced total distance traveled and reduced average speed .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetFLT
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2569527-64-4
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Formula Weight501.07
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Molecular FormulaC29H33ClN6
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Purity>98% (HPLC)
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Solubility——
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SMILESCC1=CC2=C(C(C3=NC(NC4=CC(CN5C[C@H](N[C@H](C5)C)C)=CC(C6CC6)=C4)=NC=C3Cl)=CN2)C=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Nail-Boucherie K, et al. The specific dopamine uptake inhibitor GBR 12783 improves learning of inhibitory avoidance and increases hippocampal acetylcholine release. Brain Res Cogn Brain Res. 1998 Oct;7(2):203-5.
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