HG106

CAS No. 928712-10-1

HG106( —— )

Catalog No. M36018 CAS No. 928712-10-1

HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 88 In Stock
5MG 140 In Stock
10MG 227 In Stock
25MG 419 In Stock
50MG 604 In Stock
100MG 826 In Stock
500MG 1647 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    HG106
  • Note
    Research use only, not for human use.
  • Brief Description
    HG106, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene, which is anti-inflammatory and may be used to treat the growth of diseases such as malignant tumours caused by mutations in the RAS gene.
  • Description
    HG106 is a potent SLC7A11 inhibitor. HG106 markedly decreased cystine uptake and intracellular glutathione biosynthesis.HG106 can be used for the research of KRAS-mutant lung adenocarcinoma.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    928712-10-1
  • Formula Weight
    316.74
  • Molecular Formula
    C15H13ClN4O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (394.65 mM; Ultrasonic )
  • SMILES
    N(C(CCl)=O)C1=CC=2C(=NN(N2)C3=CC=C(OC)C=C3)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hu K, et al. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma. J Clin Invest. 2020 Apr 1;130(4):1752-1766.?
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