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Groenlandicine
CAS No. 38691-95-1
Groenlandicine( —— )
Catalog No. M24345 CAS No. 38691-95-1
Groenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 426 | In Stock |
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| 10MG | 611 | In Stock |
|
| 25MG | 888 | In Stock |
|
| 50MG | 1242 | In Stock |
|
| 100MG | 1701 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameGroenlandicine
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NoteResearch use only, not for human use.
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Brief DescriptionGroenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR).
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DescriptionGroenlandicine is a protoberberine alkaloid from Coptidis Rhizoma. Groenlandicine exhibits moderate inhibitory effect with IC50 value of 154.2 μM for human recombinant aldose reductase (HRAR). Groenlandicine selectively induces topoisomerase I-mediated DNA cleavage;Groenlandicine may be a promising anti-Alzheimer's disease agent due to its potent inhibitory activity of both ChEs and beta-amyloids formation, as well as marked ONOO(-) scavenging and good ROS inhibitory capacities.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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Recptortopoisomerase I
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Research Area——
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Indication——
Chemical Information
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CAS Number38691-95-1
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Formula Weight322.33
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Molecular FormulaC19H16NO4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCOC1=CC2=C(C=C1O)CC[N+]3=CC4=C(C=CC5=C4OCO5)C=C23
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Research on bitter components from Coptis chinensis based on electronic tongue.Zhongguo Zhong Yao Za Zhi. 2014 Sep;39(17):3326-9.
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