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GSK3011724A
CAS No. ——
GSK3011724A( DG167 | GSK-3011724A )
Catalog No. M17106 CAS No. ——
GSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameGSK3011724A
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NoteResearch use only, not for human use.
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Brief DescriptionGSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM).
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DescriptionGSK3011724A (DG167, GSK3011724A) is a potent, specific inhibitor of β-ketoacyl-ACP synthase (KasA, Kd=9 nM), shows anti-tubercular activity (MIC H37Rv=0.8 uM); shows much weaker apparent dissociation constant for both Pks10 and Pks (Kd=1.4 uM); inhibits mycolic acid biosynthesis and shows negligible activity against a panel of unrelated proteins and 18 Gram-positive and Gram-negative bacterial species.
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In Vitro——
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In Vivo——
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SynonymsDG167 | GSK-3011724A
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight267.347
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Molecular FormulaC12H17N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-(1-methyl-1H-indazol-6-yl)butane-1-sulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kumar P, et al. MBio. 2018 Dec 18;9(6). pii: e02101-17.
2. Abrahams KA, et al. Nat Commun. 2016 Sep 1;7:12581.
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