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GSK-J2
CAS No. 1394854-52-4
GSK-J2( —— )
Catalog No. M32949 CAS No. 1394854-52-4
GSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 68 | Get Quote |
|
| 10MG | 93 | Get Quote |
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| 25MG | 155 | Get Quote |
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| 50MG | 227 | Get Quote |
|
| 100MG | 329 | Get Quote |
|
| 200MG | 488 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGSK-J2
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NoteResearch use only, not for human use.
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Brief DescriptionGSK-J2 is an inactive enantiomer of GSK-J1 that is lipophilic and serves as an inactive control for GSK-J21.
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DescriptionGSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
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In VitroGSK-J2 is an isomer of GSK-J1, and shows poor activity towards KDM6A and KDM6B, with IC50 of > 100 μM and 49 μM, respectively.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number1394854-52-4
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Formula Weight389.45
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Molecular FormulaC22H23N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 42 mg/mL (107.84 mM )
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SMILESO=C(O)CCNC=1N=C(N=C(C1)N2CCC=3C=CC=CC3CC2)C4=CN=CC=C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Heinemann B, et al. Inhibition of demethylases by GSK-J1/J4. Nature. 2014 Oct 2;514(7520):E1-2?
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