Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Hedgehog (Hh) - GSA-10

GSA-10

CAS No. 300833-95-8

GSA-10( —— )

Catalog No. M27632 CAS No. 300833-95-8

GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 177 Get Quote
5MG 282 Get Quote
10MG 421 Get Quote
25MG 678 Get Quote
50MG 888 Get Quote
100MG 1251 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    GSA-10
  • Note
    Research use only, not for human use.
  • Brief Description
    GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts.
  • Description
    GSA-10 is a potent Smoothened (Smo) receptor agonist with an EC50 of 1.2 μM. It acts on Smo to promote the differentiation of pluripotent mesenchymal stem cells into osteoblasts. It also mediates Hedgehog (Hh) signaling, which may have research implications for regenerative medicine in cancer diseases.
  • In Vitro
    Western Blot Analysis Cell Line:3T3-L1 preadipocyte Concentration:10 μM Incubation Time: 24 h Result:Significantly promoted the phosphorylation of Ampk.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Hedgehog (Hh)
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    300833-95-8
  • Formula Weight
    450.535
  • Molecular Formula
    C26H30N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 1.67 mg/mL (3.71 mM)
  • SMILES
    CCCCCCn1c2ccccc2c(O)c(C(=O)Nc2ccc(cc2)C(=O)OCCC)c1=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Di Maio F, et al. Activity of creatinol O-phosphate on persistent ventricular premature beats in ischemic heart disease. Double blind clinical trial. Arzneimittelforschung. 1979;29(9a):1488-1490.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Cucurbitacin B

    Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN.

  • BRD9526

    BRD9526 is a potent, small-molecule inhibitor of the Sonic Hedgehog (Shh) pathway with EC50 of 60 nM.

  • SANT 2

    SANT 2 is a Hedgehog (Hh) signaling pathway antagonist with potential anti-inflammatory and anticancer activity for the study of prostate, pancreatic and breast cancer.

Sign In Join Free